Publications by Year
2023
Lin YH, Zeng Q, Jia Y, Wang Z, Li L, Hsieh MH, Cheng Q, Pagani CA, Livingston N, Lee J, Zhang Y, Sharma T, Siegwart DJ, Yimlamai D, Levi B, Zhu H. In vivo screening identifies SPP2, a secreted factor that negatively regulates liver regeneration. Hepatology. 2023. doi: 10.1097/HEP.0000000000000402.
Luukkonen PK, Sakuma I, Gaspar RC, Mooring M, Nasiri A, Kahn M, Zhang XM, Zhang D, Sammalkorpi H, Penttilä AK, Orho-Melander M, Arola J, Juuti A, Zhang X, Yimlamai D, Yki-Järvinen H, Petersen KF, Shulman GI. Inhibition of HSD17B13 protects against liver fibrosis by inhibition of pyrimidine catabolism in nonalcoholic steatohepatitis. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2217543120. doi: 10.1073/pnas.2217543120.
2022
Yao, K., Tarabra, E., Sia, D., Morotti, R., Fawaz, R., Valentino, P., Santoro, N., Caprio, S., Liu, S., Yimlamai, D. Transcriptomic profiling of a multiethnic pediatric NAFLD cohort reveals genes and pathways associated with disease. Hepatol Commun. 2022 Mar 21. doi: 10.1002/hep4.1940.
Toothaker, J.M., Olaloye, O., McCourt, B.T., McCourt, C.C., Silva, T.N., Case, R.M., Liu, P., Yimlamai, D., Tseng, G., Konnikova, L. Immune landscape of human placental villi using single-cell analysis. Development. 2022 Apr 15;149(8):dev200013. doi: 10.1242/dev.200013.
2021
Chen A, Jiang Y, Li Z, Wu L, Santiago U, Zou H, Cai C, Sharma V, Guan Y, McCarl LH, Ma J, Wu YL, Michel J, Shi Y, Konnikova L, Amankulor NM, Zinn PO, Kohanbash G, Agnihotri S, Lu S, Lu X, Sun D, Gittes GK, Wang Q, Xiao X, Yimlamai D, Pollack IF, Camacho CJ, Hu B. Chitinase-3-like-1 protein complexes modulate macrophage-mediated immune suppression in glioblastoma. J Clin Invest. 2021 Jul 6:147552. doi: 10.1172/JCI147552.
2020
Mooring, M. Fowl, B.H. Lum, S.Z.C., Liu, Y., Softic, S. , Kirchner, R., Bernstein, A. Singhi, A.D., Jay, D.G., Kahn, C.R., Camargo, F.D., Yimlamai, D. Hepatocyte Stress Increases Expression of YAP and TAZ in Hepatocytes to Promote Parenchymal Inflammation and Fibrosis. Hepatology. 2020. 71(5):1813-1830. PMID: 31505040.
Wen, L., Javed, T.A., Dobbs, A.K., Brown, R., Niu, M., Li, L., Khalid, A., Xiao, X., Yimlamai, D., Konnikova, L., Byersdorfer, C.A., Husain., S.Z. Protective Effects of Calcineurin on Pancreatitis in Mice Depend on Cellular Source. Gastroenterology. 2020 May 20;. doi: 10.1053/j.gastro.2020.05.051. PMID: 32445858.
Alsamman, S., Christenson, S.A., Yu, A., Ayad, N., Mooring, M.S, Segal, J., Hu, Jimmy Kuang-Hsien, Schaub, J.R., Ho, S.S., Rao, V., Marlow, M.M., Turner, S.M., Sedki, M., Rubino, L.P., Ghoshal, S., Ferreira, D.D.S., Ma, H-Y, Duwaerts, C.C., Espanol-Suner, R., Wei, L., Newcomb, B., Mileva, I., Canals, D., Hannun, Y. Chung, R.T., Mattis, A.N., Fuchs, B.C. Tager, A.M., Yimlamai, D., Weaver, V.M., Mullen, A.C., Sheppard, D.*, Chen, J.Y*. Targeting Acid Ceramidase Inhibits YAP/TAZ Signaling to Reduce Fibrosis. Sci Transl Med. 12(557):eaay8798. doi: 10.1126/scitranslmed.aay8798. PMID: 32817366
Zhang, Y., Guillermier, C., De Raedt, T., Cox, A.G., Maertens, O., Yimlamai, D., Lun, M., Whitney, A., Maas, R., Goessling., W., Cichowski, K., Steinhauser, M. Imaging mass spectrometry reveals tumor metabolic heterogeneity. iScience. 23(8):101355. PMID: 32712466.
Airik M, Schüler M, McCourt B, Weiss AC, Herdman N, Lüdtke TH, Widmeier E, Stolz DB, Nejak-Bowen KN, Yimlamai D, Wu YL, Kispert A, Airik R, Hildebrandt F. Loss of Anks6 leads to YAP deficiency and liver abnormalities. Hum Mol Genet. 2020. 29(18):3064-3080. doi: 10.1093/hmg/ddaa197. PMID: 32886109.
2019
Liu, H., Zhang, C.H., Ammanamanchi, N., Suresh, S., Lewarchik, C., Rao, K., Uys, G.M., Han, L., Abrial, M., Yimlamai, D., Ganapathy, B., Guillermier, C., Chen, N., Khaladkar, M., Spaethling, J., Eberwine, J.H., Kim, J., Walsh, S., Choudhury, S., Little, K., Francis, K., Sharma, M., Viegas, M., Bais, A., Kostka, D., Ding, J., Bar-Joseph, Z., Wu, Y., Steinhauser, M.L., Kühn, B. Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment. Sci Transl Med. 2019. 11(513). PMID: 31597755.
2018
Wen, L., Javed, T.A., Yimlamai, D., Mukherjee, A., Xiao, X., Husain, S.Z. Transient High Pressure in Pancreatic Ducts Promotes Inflammation and Alters Tight Junctions via Calcineurin Signaling in Mice. Gastroenterology. 2018. 155(4):1250-1263. PMID: 29928898.
Cox, A.G., Tsomides, A., Yimlamai, D., Hwang, K., Miesfeld, J., Galli, G., Fowl, B., Fort, M., Ma, K., Sullivan, M., Hosios, A., Snay, E., Yuan, M., Brown, K., Lien, E., Chhangawala, S., Steinhauser, M., Asara, J.M., Houvras, Y., Link, B.A., Vander Heiden, M.G., Camargo, F.D., Goessling, W. Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth. EMBO J. 2018. 37(22). pii: e100294. doi: 10.15252/embj.2018100294. PMID: 30348863.
2016
Cox, A.G.*, Hwang, K.L.*, Evason, K., Brown, K.K., Beltz, S., O’Connor, K., Galli, G.G., Tsomides, A., Yimlamai, D., Chhangawala, S., Yuan, M, Lien, E., Wucherpfennig, J., Nissim, S., Minami, A., Cohen, D.E., Camargo, F.D., Asara, J., Houvras, Y., Stainier, D.Y., Goessling, W. Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth. Nature Cell Biology. 2016. 18:886–896. PMID: 27428308.
2014
Yimlamai, D.*, Christodoulou, C.*, Galli, G.G., Yanger, K., Pepe-Mooney, B., Gurung, B., Shrestha, K., Cahan, P., Stanger, B.Z., Camargo, F.D. Hippo Pathway Activity Influences Liver Cell Fate. Cell. 2014. 157:1324-1338. PMID: 24906150.
Ganem, N.J.*, Cornils, H.*, Chiu, S-Y., O_Rourke, K.P., Arnaud, J., Yimlamai, D., Thiery, M., Camargo, F.D., Pellman, D. Cytokinesis Failure Triggers Hippo Tumor Suppressor Pathway Activation. Cell. 2014. 158:833-848. PMID: 25126788.
2013
Yimlamai, D., Freiberger, D.A., Gould, A., Zhou, J., Boyer, D. Pre-transplant Six Minute Walk Test Predicts Peri- and Post-operative Outcomes after Pediatric Lung Transplantation. Pediatric Transplantation. 2013. 17(1):34-40. PMID: 23067306.
2012
Tumaneng, K, Schlegelmilch, K, Russell, R.C., Yimlamai, D., Basnet, H., Mahadevan, N., Fitamant, J., Bardeesy, N., Camargo, F.D, Guan, K-L. YAP mediates crosstalk between the Hippo and PI3K-TOR pathways by suppressing PTEN via miR-29. Nature Cell Biology. 2012. 14(12):1322-1329. PMID: 23143395.
2005
Yimlamai, D., Konnikova, L., Moss, L.G., Jay, D.G. The zebrafish down syndrome cell adhesion molecule is involved in cell movement during embryogenesis. Developmental Biology. 2005. 279(1):44-57. PMID: 15708557.
2004
Eustace, B.K., Sakurai, T., Stewart, J.K., Yimlamai, D., Unger, C., Zehetmeier, C., Lain, B., Torella, C., Henning, S.W., Beste, G., Scroggins, B.T., Neckers, L., Ilag, L.L., Jay, D.G. Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasiveness. Nature Cell Biology. 2004. 6(6):507-514. PMID: 15146192.
2002
Diefenbach, T.J.*, Latham, V.M.*, Yimlamai, D., Liu, C.A., Herman, I.M., Jay, D.G. Myosin 1c and myosin IIB serve opposing roles in lamellipodial dynamics of the neuronal growth cone. Journal of Cell Biology. 2002. 158(7):1207-1217. PMID: 12356865.
1999
Korenberg, J.R., Chen, X-N., Sun, Z, Shi, Z.Y., Ma, A, Vataru, E., Yimlamai, D., Weissenbach, J.S., Shizuya, H., Simon, M.I., Gerety, S.S., Nguyen, H., Zemsteva, I.S., Hui, L., Silva, J., Wu, X., Birren, B.W., Hudson, T.J. Human genome anatomy: BACs integrating the genetic and cytogenetic maps for bridging genome and biomedicine. Genome Research. 1999. 9(10):994-1001. PMID: 10523528.
Lin YH, Zeng Q, Jia Y, Wang Z, Li L, Hsieh MH, Cheng Q, Pagani CA, Livingston N, Lee J, Zhang Y, Sharma T, Siegwart DJ, Yimlamai D, Levi B, Zhu H. In vivo screening identifies SPP2, a secreted factor that negatively regulates liver regeneration. Hepatology. 2023. doi: 10.1097/HEP.0000000000000402.
Luukkonen PK, Sakuma I, Gaspar RC, Mooring M, Nasiri A, Kahn M, Zhang XM, Zhang D, Sammalkorpi H, Penttilä AK, Orho-Melander M, Arola J, Juuti A, Zhang X, Yimlamai D, Yki-Järvinen H, Petersen KF, Shulman GI. Inhibition of HSD17B13 protects against liver fibrosis by inhibition of pyrimidine catabolism in nonalcoholic steatohepatitis. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2217543120. doi: 10.1073/pnas.2217543120.
2022
Yao, K., Tarabra, E., Sia, D., Morotti, R., Fawaz, R., Valentino, P., Santoro, N., Caprio, S., Liu, S., Yimlamai, D. Transcriptomic profiling of a multiethnic pediatric NAFLD cohort reveals genes and pathways associated with disease. Hepatol Commun. 2022 Mar 21. doi: 10.1002/hep4.1940.
Toothaker, J.M., Olaloye, O., McCourt, B.T., McCourt, C.C., Silva, T.N., Case, R.M., Liu, P., Yimlamai, D., Tseng, G., Konnikova, L. Immune landscape of human placental villi using single-cell analysis. Development. 2022 Apr 15;149(8):dev200013. doi: 10.1242/dev.200013.
2021
Chen A, Jiang Y, Li Z, Wu L, Santiago U, Zou H, Cai C, Sharma V, Guan Y, McCarl LH, Ma J, Wu YL, Michel J, Shi Y, Konnikova L, Amankulor NM, Zinn PO, Kohanbash G, Agnihotri S, Lu S, Lu X, Sun D, Gittes GK, Wang Q, Xiao X, Yimlamai D, Pollack IF, Camacho CJ, Hu B. Chitinase-3-like-1 protein complexes modulate macrophage-mediated immune suppression in glioblastoma. J Clin Invest. 2021 Jul 6:147552. doi: 10.1172/JCI147552.
2020
Mooring, M. Fowl, B.H. Lum, S.Z.C., Liu, Y., Softic, S. , Kirchner, R., Bernstein, A. Singhi, A.D., Jay, D.G., Kahn, C.R., Camargo, F.D., Yimlamai, D. Hepatocyte Stress Increases Expression of YAP and TAZ in Hepatocytes to Promote Parenchymal Inflammation and Fibrosis. Hepatology. 2020. 71(5):1813-1830. PMID: 31505040.
Wen, L., Javed, T.A., Dobbs, A.K., Brown, R., Niu, M., Li, L., Khalid, A., Xiao, X., Yimlamai, D., Konnikova, L., Byersdorfer, C.A., Husain., S.Z. Protective Effects of Calcineurin on Pancreatitis in Mice Depend on Cellular Source. Gastroenterology. 2020 May 20;. doi: 10.1053/j.gastro.2020.05.051. PMID: 32445858.
Alsamman, S., Christenson, S.A., Yu, A., Ayad, N., Mooring, M.S, Segal, J., Hu, Jimmy Kuang-Hsien, Schaub, J.R., Ho, S.S., Rao, V., Marlow, M.M., Turner, S.M., Sedki, M., Rubino, L.P., Ghoshal, S., Ferreira, D.D.S., Ma, H-Y, Duwaerts, C.C., Espanol-Suner, R., Wei, L., Newcomb, B., Mileva, I., Canals, D., Hannun, Y. Chung, R.T., Mattis, A.N., Fuchs, B.C. Tager, A.M., Yimlamai, D., Weaver, V.M., Mullen, A.C., Sheppard, D.*, Chen, J.Y*. Targeting Acid Ceramidase Inhibits YAP/TAZ Signaling to Reduce Fibrosis. Sci Transl Med. 12(557):eaay8798. doi: 10.1126/scitranslmed.aay8798. PMID: 32817366
Zhang, Y., Guillermier, C., De Raedt, T., Cox, A.G., Maertens, O., Yimlamai, D., Lun, M., Whitney, A., Maas, R., Goessling., W., Cichowski, K., Steinhauser, M. Imaging mass spectrometry reveals tumor metabolic heterogeneity. iScience. 23(8):101355. PMID: 32712466.
Airik M, Schüler M, McCourt B, Weiss AC, Herdman N, Lüdtke TH, Widmeier E, Stolz DB, Nejak-Bowen KN, Yimlamai D, Wu YL, Kispert A, Airik R, Hildebrandt F. Loss of Anks6 leads to YAP deficiency and liver abnormalities. Hum Mol Genet. 2020. 29(18):3064-3080. doi: 10.1093/hmg/ddaa197. PMID: 32886109.
2019
Liu, H., Zhang, C.H., Ammanamanchi, N., Suresh, S., Lewarchik, C., Rao, K., Uys, G.M., Han, L., Abrial, M., Yimlamai, D., Ganapathy, B., Guillermier, C., Chen, N., Khaladkar, M., Spaethling, J., Eberwine, J.H., Kim, J., Walsh, S., Choudhury, S., Little, K., Francis, K., Sharma, M., Viegas, M., Bais, A., Kostka, D., Ding, J., Bar-Joseph, Z., Wu, Y., Steinhauser, M.L., Kühn, B. Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment. Sci Transl Med. 2019. 11(513). PMID: 31597755.
2018
Wen, L., Javed, T.A., Yimlamai, D., Mukherjee, A., Xiao, X., Husain, S.Z. Transient High Pressure in Pancreatic Ducts Promotes Inflammation and Alters Tight Junctions via Calcineurin Signaling in Mice. Gastroenterology. 2018. 155(4):1250-1263. PMID: 29928898.
Cox, A.G., Tsomides, A., Yimlamai, D., Hwang, K., Miesfeld, J., Galli, G., Fowl, B., Fort, M., Ma, K., Sullivan, M., Hosios, A., Snay, E., Yuan, M., Brown, K., Lien, E., Chhangawala, S., Steinhauser, M., Asara, J.M., Houvras, Y., Link, B.A., Vander Heiden, M.G., Camargo, F.D., Goessling, W. Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth. EMBO J. 2018. 37(22). pii: e100294. doi: 10.15252/embj.2018100294. PMID: 30348863.
2016
Cox, A.G.*, Hwang, K.L.*, Evason, K., Brown, K.K., Beltz, S., O’Connor, K., Galli, G.G., Tsomides, A., Yimlamai, D., Chhangawala, S., Yuan, M, Lien, E., Wucherpfennig, J., Nissim, S., Minami, A., Cohen, D.E., Camargo, F.D., Asara, J., Houvras, Y., Stainier, D.Y., Goessling, W. Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth. Nature Cell Biology. 2016. 18:886–896. PMID: 27428308.
2014
Yimlamai, D.*, Christodoulou, C.*, Galli, G.G., Yanger, K., Pepe-Mooney, B., Gurung, B., Shrestha, K., Cahan, P., Stanger, B.Z., Camargo, F.D. Hippo Pathway Activity Influences Liver Cell Fate. Cell. 2014. 157:1324-1338. PMID: 24906150.
Ganem, N.J.*, Cornils, H.*, Chiu, S-Y., O_Rourke, K.P., Arnaud, J., Yimlamai, D., Thiery, M., Camargo, F.D., Pellman, D. Cytokinesis Failure Triggers Hippo Tumor Suppressor Pathway Activation. Cell. 2014. 158:833-848. PMID: 25126788.
2013
Yimlamai, D., Freiberger, D.A., Gould, A., Zhou, J., Boyer, D. Pre-transplant Six Minute Walk Test Predicts Peri- and Post-operative Outcomes after Pediatric Lung Transplantation. Pediatric Transplantation. 2013. 17(1):34-40. PMID: 23067306.
2012
Tumaneng, K, Schlegelmilch, K, Russell, R.C., Yimlamai, D., Basnet, H., Mahadevan, N., Fitamant, J., Bardeesy, N., Camargo, F.D, Guan, K-L. YAP mediates crosstalk between the Hippo and PI3K-TOR pathways by suppressing PTEN via miR-29. Nature Cell Biology. 2012. 14(12):1322-1329. PMID: 23143395.
2005
Yimlamai, D., Konnikova, L., Moss, L.G., Jay, D.G. The zebrafish down syndrome cell adhesion molecule is involved in cell movement during embryogenesis. Developmental Biology. 2005. 279(1):44-57. PMID: 15708557.
2004
Eustace, B.K., Sakurai, T., Stewart, J.K., Yimlamai, D., Unger, C., Zehetmeier, C., Lain, B., Torella, C., Henning, S.W., Beste, G., Scroggins, B.T., Neckers, L., Ilag, L.L., Jay, D.G. Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasiveness. Nature Cell Biology. 2004. 6(6):507-514. PMID: 15146192.
2002
Diefenbach, T.J.*, Latham, V.M.*, Yimlamai, D., Liu, C.A., Herman, I.M., Jay, D.G. Myosin 1c and myosin IIB serve opposing roles in lamellipodial dynamics of the neuronal growth cone. Journal of Cell Biology. 2002. 158(7):1207-1217. PMID: 12356865.
1999
Korenberg, J.R., Chen, X-N., Sun, Z, Shi, Z.Y., Ma, A, Vataru, E., Yimlamai, D., Weissenbach, J.S., Shizuya, H., Simon, M.I., Gerety, S.S., Nguyen, H., Zemsteva, I.S., Hui, L., Silva, J., Wu, X., Birren, B.W., Hudson, T.J. Human genome anatomy: BACs integrating the genetic and cytogenetic maps for bridging genome and biomedicine. Genome Research. 1999. 9(10):994-1001. PMID: 10523528.